Prostate Cancer: Screening, Diagnosis & Staging – Complete Guide
📚 All Prostate Cancer Topics (Screening, Diagnosis & Staging)
Prostate Cancer Symptoms
Early cancer has NO symptoms. Learn about signs of advanced disease (bone pain, weight loss, urinary symptoms).
Prostate Cancer Risk Factors
Age, family history, genetics (BRCA, HOXB13), race, diet, and lifestyle factors that increase risk.
PSA Screening Guidelines
AUA, USPSTF, NCCN recommendations – when to start, how often, and when to stop.
PSA Levels by Age
Normal PSA ranges by age decade, age-specific thresholds, and what abnormal results mean.
PSA Density & Velocity
How rate of change and prostate size affect PSA interpretation – when to worry.
MRI for Prostate Cancer Detection
Multiparametric MRI (mpMRI) – PI-RADS scores, sensitivity, and when it's used.
Prostate Biopsy (MRI-Fusion)
TRUS biopsy, MRI-targeted fusion biopsy, transperineal vs. transrectal, risks, and preparation.
Gleason Score & Grade Groups
How prostate cancer is graded – Gleason score (6-10) and ISUP Grade Groups (1-5).
Prostate Cancer Staging (TNM)
TNM staging – Tumor (T1-T4), Nodes (N0-N1), Metastasis (M0-M1c). Risk groups (low, intermediate, high).
Genetic Testing (BRCA, HOXB13)
When to consider genetic testing – hereditary prostate cancer syndromes and implications.
Prostate Cancer in Young Men
Early-onset prostate cancer (<55 years) – risk factors, genetics, and aggressive features.
Prostate Cancer in Elderly Men
Balancing screening benefits with life expectancy – when to screen and when to stop.
Active Surveillance for Prostate Cancer
For low-risk cancer – monitoring with PSA, MRI, and repeat biopsies. When to treat.
Prostate Cancer Risk Calculator
Online tools (PCPT, ERSPC) that estimate your risk of cancer and high-grade disease.
Prostate Cancer Second Opinion
When to seek a second opinion – pathology review, treatment options, and specialist referrals.
🎯 Who Should Read This Section?
- Men considering PSA screening – Understand the benefits and harms of screening.
- Men with elevated PSA or abnormal DRE – Learn about next steps (MRI, biopsy).
- Men newly diagnosed with prostate cancer – Understand your Gleason score, stage, and risk group.
- Men with family history of prostate cancer – Learn about genetic testing and early screening.
- Medical students and trainees – Build clinical knowledge of prostate cancer diagnosis and staging.
🔗 Related Pillars
- Pillar 1: Prostate Basics – Anatomy, function, PSA test, DRE.
- Pillar 2: BPH (Enlarged Prostate) – Benign enlargement vs. cancer.
- Pillar 5: Prostate Cancer Treatment – Surgery, radiation, hormone therapy.
Disclaimer: This information is for educational purposes. Prostate cancer screening and diagnosis should be discussed with a urologist. At Vivekananda Hospital, we offer comprehensive prostate cancer care – from screening to treatment.